Potential of Miana Leaves (Coleus scutellarioides (L.) Benth) As an Antibacterial Streptococcus pneumonia, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumonia from Sputum Cough Patients in Makassar City
Preliminary. The high intensity of a cough attack is an indication of a respiratory disorder or infection in the throat. Phlegm in coughing indicates infection and inflammation of the respiratory tract. Cough-causing bacteria include Streptococcus pneumonia, Klebsiella pneumonia, Staphylococcus aureus, Staphylococcus epidermidis. The aim of the study was to prove the potential of Miana leaves as an antibacterial cause of cough in vitro. Method. The test bacteria Streptococcus pneumonia, Klebsiella pneumonia, Staphylococcus aureus, Staphylococcus epidermidis are the result of isolation and identification of cough sufferers sputum in Ibnu Sina Hospital Makassar. Sputum samples were taken randomly for a period of 2 weeks. Miana leaves are obtained from Tana Toraja Regency and extracted using a juicer. Antibacterial antibacterial testing was carried out by agar diffusion method. Blank paper disc was soaked in miana leaf extract, cefadroxil, amoxicillin and distilled water as negative control, then placed on the surface of the media containing test bacteria. The inhibition zone is measured as an antibacterial activity. Results. Miana leaf extract can inhibit and kill the growth of Streptococcus pneumonia bacteria, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumonia. Miana leaf extract provides a better zone of bacterial growth inhibition than amoxicillin and cefradoxyl. Diameter of inhibition zone of miana leaf extract 25,3 - 28,7mm; cefadroksil 16,6 - 21mm and amoxicillin 11,6 - 20mm. Conclusion. Miana leaf extract has the potential as an antibacterial for Streptococcus pneumonia, Staphylococcus aureus, Staphylococcus epidermidis, Klebsiella pneumonia which causes coughing.